A comprehensive, non-redundant catalogue of human PIWI-interacting RNAs integrating sequences from seven major piRNA repositories (piRBase, piRNABank, piRNAdb, piRNAQuest, NCBI, piOxiDB, and proTRAC) — with coordinate verification, isoform collapse, genomic annotation, and ping-pong relationship mapping.
All major piRNA databases integrated and deduplicated into a single canonical sequence per unique piRNA, with stable IDs across database versions.
Every piRNA's genomic coordinates verified against hg38 using a 3-level strategy: exact match, Bowtie2 alignment, and STAR alignment.
piRNAs grouped into families by 5′ anchor alignment. Each family has a designated root sequence with isoforms catalogued by variant type and Hamming distance.
Antisense partner relationships detected and catalogued at the sequence level, with HIGH/LOW confidence tiers and 10-nt seed indexing.
Every piRNA annotated for transposable element overlap, gene context (biotype, region, strand), miRNA overlap, and de novo cluster membership.
Search by sequence, ID, alias (piR-hsa-XXXXXX), gene name, TE family, miRNA name, or genomic cluster. FTS5-indexed for sub-second response.