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piRNAome Database Overview

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Total piRNAs
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Families
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Known Clusters
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De Novo Clusters
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SNV Annotated
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Junction Candidates
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Ping-pong Pairs
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1U Primary
SNV Interpretation
Genomic Context
De Novo Cluster Tiers
Quality Distribution
Family Size Distribution
Source Databases
Isoform Confidence
Verification Status

Data Sources

Every annotation in piRNAome is traceable to a published external resource. Versions reflect the snapshot ingested for the current release.

piRNA Primary Sources
piRBase v3.0 — sequence-verified piRNAs, gold-standard IDs
piRNABank — sequence corpus, multi-species
piRNAdb v1.7.6 — curated piRNA catalog
piRNAQuest v2.0 — clinically-relevant piRNA collection
SNV Interpretation
dbSNP build 151 — common population variants (snp151Common)
ClinVar — clinical variant interpretations
REDIportal v3 — A-to-I RNA editing sites (TABLE1 hg38)
COSMIC v104 — somatic mutations (coding + non-coding, tumor + matched normal)
Genomic Annotations
GENCODE v49 — gene models (coding + ncRNA)
Dfam / RepeatMasker — transposable element families (hg38)
miRBase v22 — miRNA loci & mature sequences
UCSC hg38 / GRCh38 — primary assembly reference
Pipeline: sequence compilation across four piRNA databases → Bowtie2 / STAR genome verification on hg38 → multi-database family clustering → annotation pass (gene / TE / miRNA / SNV / RNA-editing / somatic) → de novo cluster discovery (per-chromosome Poisson model) → TE-aware sub-family splitting. All scripts are open source.

Genome-wide piRNA Distribution Full Browser →